Beer Sheva scored the only goal after just four minutes of play with a penalty from Portuguese midfielder Josue, after Plzen's goalkeeper Ales Hruska fouled Colombian striker Jhonatan Agudelo.
Chelsea fought back from 3-0 down away to West Brom to claim a 3-3 draw thanks to an injury-time goal from Tammy Abraham.
Icardi found the target in each half thanks to two assists from French international Kylian Mbappe.
Miguel Angel Russo's men are now four points clear at the top of the Group H standings, with one match remaining before the knockout rounds.
Pepe has scored four goals in his past five matches for Gremio, including two in the Copa Libertadores against Internacional and Universidad Catolica.
Wuhan Zall had no chances to enter the championship race after losing to Hebei China Fortune 2-0, while Tianjin enlarged its winless record to 13 games after being defeated by Qingdao Huanghai 3-0 before the match.
"Elite edition of the Valencia marathon and half marathon will be held on Dec. 6, we can now confirm the names of the first male and female athletes who will seek to achieve the most ambitious sporting goal possible by trying to set new race records," the organizers said in a statement.
"We haven't played an official game for a long time, so players were kind of excited, and we transferred a lot of positive energy on the court," Shandong coach Luka Sjekloca noted.
In 2019 he signed with the Milwaukee Bucks and this year he joined the Warriors.
Second seed Nadal will face Italy's Stefano Travaglia in the round of 32. The latter survived a five-set thriller against Japan's Nishikori Kei to advance 6-4, 2-6, 7-6 (7), 4-6, 6-2.
TOKYO, Sept. 28 (Xinhua) -- The route and schedule of the torch relay for the postponed Tokyo Olympic and Paralympic Games will remain as originally planned, the Tokyo 2020 organizers announced here on Monday.