Slovenia's Roglic arrived with the leading group to remain 21 seconds ahead of defending champion Egan Bernal on the overall standings.
This was Van Aert's second stage win in the race, after the Jumbo all-rounder had also triumphed in stage five.
Pepe has made 99 appearances for Gremio and scored 21 goals since making his professional debut in 2017.
Poland now travel to play Bosnia and Herzegovina on Monday, while the Netherlands face Italy. Enditem
In the other two games of the day, Shenzhen Nankeda overwhelmed Anhui Souyu 5-0, while Jiangsu Weikeduo lost to Xiamen Tefang 3-2, still striving for a win this season. Enditem
In the women's singles, fourth seed Naomi Osaka of Japan finished a routine job as she eased past Anett Kontaveit from Estonia 6-3, 6-4 to reach the quarterfinals.
Shenzhen will also face another huge loss in the clash with defending champions since Mary got a red card and was sent off the pitch in the stoppage time due to his aggressive language to Shanghai head coach Choi Kang-Hee.
A lonely Lutsenko sprinted to the finish and had to wait 55 seconds before the second rider Herrada appeared.
After the defeat, Brzeczek surprised the waiting journalists by praising his team.
In the 93rd minute, R&F's goalkeeper Han Jiaqi failed to clear out the ball from the box, giving Paulinho an opportunity to add a buzzer beater for Evergrande.
Leon are now a point clear of second-placed Cruz Azul, who will have the chance to regain top spot when they visit Atlas on Saturday.