Mohamed Salah scored two penalties in a hat-trick as reigning champions Liverpool beat newly promoted Leeds United 4-3 in a thrilling game at Anfield, while Wilfred Zaha's 13th minute goal gave Crystal Palace a winning start at home over Southampton and new boys Callum Wilson and Jeff Hendricks both scored as Newcastle cruised past a poor West Ham in the London Stadium.
The anarchy in injury time started with a tussle between Argentine pair Dario Benedetto of Marseille and Leandro Paredes of PSG, as the two players were both shown their second yellow cards and were sent off.
On the other side of Manchester, Ole Gunnar Solskjaer can be reasonably satisfied after a season that looked destined to end in total mediocrity finished with a third-place finish and a Europa League semi-final appearance.
In other fixtures on Thursday, Palmeiras won 2-0 at Corinthians and Atletico Goianiense beat Vasco da Gama 2-1 in Rio de Janeiro. Enditem
The fact that those results can be seen as positive shows how far United have fallen since their glory days but the arrival of Donny van de Beek from Ajax should add further depth and control to Solskjaer's midfield, while Mason Greenwood's rapid progress alongside Anthony Martial and Marcos Rashford in attack, means they will be tough to defend against even if doubts remain about United's own back line.
Ribamar Lopes put the visitors ahead from close range after some shambolic Botafogo defending but Matheus Rabi equalized with a 25-yard drive just after half time.
Meanwhile the arrival of the experienced Manuel Pellegrini at Betis promises the stability that has been missing at the club in recent seasons and that alone should improve a team that underperformed last time around.
In contrast, Dele Ali disappointed for Tottenham and was replaced at the break and it is the first time Mourinho has been beaten in the first league game of the season in his entire career.
Meanwhile, playing in front of empty stands (for the opening months of the campaign at least) once again promises to make a mockery of home advantage and make games much harder to predict.
Iran sit third, behind Iraq and Bahrain, in Group C of the 2022 FIFA World Cup Asian Zone qualification. Enditem
"Javier has reached China on Friday, and he will join the team after quarantine. We hope Javier will lead the team to overcome difficulties to win more," the club said in a statement.